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The Cell Freezing Media Market size was estimated at USD153.59 million in 2023 and is expected to reach USD 351.34 million by 2032 with a growing CAGR of 9.63% during the forecast period of 2024-2032.
A cryoprotective substance, such as dimethylsulfoxide (DMSO) or glycerol, should be present in the cell freezing media. It is a full-service cell freezing medium designed specifically for mammalian cell cultures. However, because DMSO is a recognized carcinogen and mutagen, DMSO-free formulations are becoming attractive for stem cell applications. This is especially important for cells employed in translational research or clinical applications.
DRIVERS
Investment in cell culture research and development for the creation of tailored medicines has expanded dramatically in recent years. Numerous companies are investing in cell culture technology, presenting a possibility for market expansion in the near future. This increased usage of harvesting in cell culture to treat a variety of ailments is projected to drive market expansion in the near future. All of these technological advancements, as well as increased R&D spending, are projected to accelerate the market's expansion in the approaching years.
The growing acceptance of cell culture in cancer treatment, drug discovery, and vaccine development has increased financing for cell-based research. However, the costs required for cell-based research are very high, thus financing for these studies has been promoted in just a few industrialized countries, such as the United States and the United Kingdom. As financing for cell-based research grows, the potential for augmentation of the cell harvesting businesses are likely to grow dramatically in the near future.
RESTRAIN
The high costs of cryopreservation and cell freezing media
Strict Regulatory Standards for Cell-Based Products and Cryopreservation Systems
OPPORTUNITY
Advances in cell freezing media formulation and cryopreservation techniques, as well as leveraged uses of cell freezing media in disciplines such as tissue engineering, cellular treatment, and stem cell research, have driven the industry at a significant rate. Furthermore, supporting government laws for regenerative medicine and cell-based research is expected to boost the global market. For example, in June 2021, researchers from Sydney will receive money from the MRFF to pioneer stem cell research for the treatment of patients with end-stage heart failure.
CHALLENGES
IMPACT OF RUSSIA-UKRAINE WAR
In terms of the global pharma business, the war's influence has been limited to pharma manufacturers' investments and operations, as well as exporters' market interests in Russia, Ukraine, and other CIS nations, a potentially transient and fleeting phenomenon. This is also due to the fact that Russia and Ukraine are predominantly pharma importing countries, implying that global pharma is not overly reliant on this region for essential raw materials and supplies. Indeed, some multinational pharmaceutical corporations have reduced their activities in Russia. However, there is some substance to the notion that the pharmaceutical sector is dependent on oil and gas not just for transportation and logistics, but also because a substantial number of pharmaceutical goods are derived from petrochemicals.
IMPACT OF ONGOING RECESSION
Historically, the healthcare business was generally recession-proof because commercial insurers served as a buffer by paying far more for treatments than government programs. High unemployment and consumer-driven health insurance have changed that dynamic. Access to alternative forms of treatment has also contributed to economic uncertainty. Many health-care facilities transitioned to a digital landscape in the aftermath of the pandemic, owing to the requirement for distant work and treatment. Indeed, online-focused startups generated more than $29 billion in 2021 alone, necessitating more roles for IT specialists.
By Product
In 2022, DMSO segment is accounted the largest market share of over 51.6% during the forecast period. This is owing to the gold standard set over years of employing DMSO in classical cryopreservation for halting cell metabolic activity. Because of its aprotic and solvation characteristics, DMSO is a key role in cryobiology. Because it suppresses the production of ice crystals both intracellularly and extracellularly at sub-zero temperatures during slow freezing, DMSO has seen broad use as a cryoprotectant.
Furthermore, it protects against biological damage during the cryopreservation procedure. As a result, several market competitors are selling a variety of DMSO-based cell freezing media, as well as alternative cell freezing media solutions. Various applications of DMSO-based cell freezing media have also contributed to its dominance in the market. Merck KGaA, for example, offers a variety of DMSO-based cryopreservation media suited for mammalian cancer cell lines and other cell lines under the Sigma Aldrich brand.
By Application
Stem Cell Lines
Cancer Cell Lines
Others
In 2022, stem cell lines segment is accounted the largest market share of over 57.6% during the forecast period, due to the increasing demand for biopharmaceuticals as a result of effective therapies such as cell and gene therapy, as well as an increase in innovation that has resulted in an increase in approvals, are the primary reasons driving category growth. Due to current clinical success rates and the product pipeline, the FDA in the United States is expected to approve 10 to 20 cell and gene therapy medicines per year by 2025. This has prompted market participants to establish a viable supply network for all consumables in light of the anticipated increase in demand in the future years. As a result, using cell freezing media for continuous processing of these therapeutic items will result in the quickest market penetration during the forecast period.
By End User
Pharmaceutical and Biotechnological Companies
Research & Academic Institutes
Others
In 2022, pharmaceutical and biotechnological companies segment is accounted the largest market share of over 42.7% during the forecast period, the segment's rise has been ascribed to the continued expansion and commercial success of biopharmaceuticals, as well as the expanding portfolio of large pharmaceutical corporations. The cell preservation medium's superior protection and preservation, as well as its cost effectiveness in comparison to standard freezing techniques, have fueled its widespread use. The continuous use of these consumables during the research, clinical, and even commercial stages is expected to contribute to market expansion.
North America held a significant market share of over 38.4% in 2022. The presence of advanced healthcare infrastructure, developed economies, significant players, and established supply channels jointly drive the industry. Furthermore, the incidence of diseases and the expanding elderly population have accelerated the race to produce innovative and efficacious remedies through the biopharmaceutical industry. This has increased demand for cell freezing media and is projected to continue generating money in the coming years.
Asia Pacific is witness to expand fastest market share of 11.8% during the forecast due to the Asia Pacific region has a supportive government, is focused on low labor and operating costs, and is a key hub for biologics manufacturing, particularly monoclonal antibodies (MAbs). MAbs are typically developed using a large number of mammalian cell cultures that are continuously processed and require cryopreservation.
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REGIONAL COVERAGE
North America
US
Canada
Mexico
Europe
Eastern Europe
Poland
Romania
Hungary
Turkey
Rest of Eastern Europe
Western Europe
Germany
France
UK
Italy
Spain
Netherlands
Switzerland
Austria
Rest of Western Europe
Asia Pacific
China
India
Japan
South Korea
Vietnam
Singapore
Australia
Rest of Asia Pacific
Middle East & Africa
Middle East
UAE
Egypt
Saudi Arabia
Qatar
Rest of Middle East
Africa
Nigeria
South Africa
Rest of Africa
Latin America
Brazil
Argentina
Colombia
Rest of Latin America
The major players are Thermo Fisher Scientific, Inc., Merck KGaA, Sartorius AG, BioLife Solutions, Inc., Bio-Techne, HiMedia Laboratories, PromoCell GmbH, Capricorn Scientific, Cell Applications, Inc., STEMCELL Technologies., AMSBIO, Cell Systems, BPS Bioscience, Inc., and Others.
In March 2023, Nucleus Biologics, Center for Breakthrough Medicines, and Stoic Bio forged a strategic partnership to ensure a consistent supply of quality-controlled cellular culture medium to aid in the development of cell and gene treatments.
In May 2022, NIBRT (National Institute of Bioprocessing Research and Training) announced, a collaboration with Kerry Group and ValitaCell to enhance the understanding and validation of cell culture media products for the Kerry Group. ValitaCell will provide its Chemstress platform for microscale biological environment simulation. This project received funding from Enterprise Ireland to support innovation.
In November 2021, Sartorius invested approximately USD 31.6 million (EUR 30 million) in Ulm, Germany, and opened a new 65,000-square-foot Cell Culture Technology Center to promote cell line research and optimize the company's cell culture media range.
|
Report Attributes |
Details |
|
Market Size in 2023 |
US$ 153.59 million |
|
Market Size by 2032 |
US$ 351.34 million |
|
CAGR |
CAGR of 9.63% From 2024 to 2032 |
|
Base Year |
2023 |
|
Forecast Period |
2024-2032 |
|
Historical Data |
2020-2022 |
|
Report Scope & Coverage |
Market Size, Segments Analysis, Competitive Landscape, Regional Analysis, DROC & SWOT Analysis, Forecast Outlook |
|
Key Segments |
Cell Freezing Media Market Size, Share and Segmentation, By Product (DMSO, Glycerol, Others), By Application (Stem Cell lines, Cancer Cell Lines, Others), By End User (Pharmaceutical and Biotechnological Companies, Research & Academic Institutes, Others) |
|
Regional Analysis/Coverage |
North America (US, Canada, Mexico), Europe (Eastern Europe [Poland, Romania, Hungary, Turkey, Rest of Eastern Europe] Western Europe] Germany, France, UK, Italy, Spain, Netherlands, Switzerland, Austria, Rest of Western Europe]), Asia Pacific (China, India, Japan, South Korea, Vietnam, Singapore, Australia, Rest of Asia Pacific), Middle East & Africa (Middle East [UAE, Egypt, Saudi Arabia, Qatar, Rest of Middle East], Africa [Nigeria, South Africa, Rest of Africa], Latin America (Brazil, Argentina, Colombia Rest of Latin America) |
|
Company Profiles |
Thermo Fisher Scientific, Inc., Merck KGaA, Sartorius AG, BioLife Solutions, Inc., Bio-Techne, HiMedia Laboratories, PromoCell GmbH, Capricorn Scientific, Cell Applications, Inc., STEMCELL Technologies., AMSBIO, Cell Systems, BPS Bioscience, Inc. |
|
Key Drivers |
•R&D in personalized medicine drives market growth |
|
Market Restrain |
•The high costs of cryopreservation and cell freezing media |
Cell Freezing Media Market is anticipated to expand by 9.63% from 2024 to 2032.
Cell Freezing Media Market is expected to grow USD 351.34 million by 2032.
Cell Freezing Media Market size was valued at USD 153.59 million in 2023.
R&D in personalized medicine drives market growth.
Issues with the usage of common cell freezing media.
Table of Contents
1. Introduction
1.1 Market Definition
1.2 Scope
1.3 Research Assumptions
2. Research Methodology
3. Market Dynamics
3.1 Drivers
3.2 Restraints
3.3 Opportunities
3.4 Challenges
4. Impact Analysis
4.1 Impact of the Ukraine- Russia War
4.2 Impact of Ongoing Recession
4.2.1 Introduction
4.2.2 Impact on major economies
4.2.2.1 US
4.2.2.2 Canada
4.2.2.3 Germany
4.2.2.4 France
4.2.2.5 United Kingdom
4.2.2.6 China
4.2.2.7 Japan
4.2.2.8 South Korea
4.2.2.9 Rest of the World
5. Value Chain Analysis
6. Porter’s 5 forces model
7. PEST Analysis
8. Cell Freezing Media Market Segmentation, By Product
8.1 DMSO
8.1.1 With Serum
8.1.2 Without Serum
8.2 Glycerol
8.2.1 With Serum
8.2.2 Without Serum
8.3 Others
9. Cell Freezing Media Market Segmentation, By Application
9.1 Stem Cell Lines
9.2 Cancer Cell Lines
9.3 Others
10. Cell Freezing Media Market Segmentation, By End User
10.1 Pharmaceutical and Biotechnological Companies
10.2 Research & Academic Institutes
10.3 Others
11. Regional Analysis
11.1 Introduction
11.2 North America
11.2.1 North America Cell Freezing Media Market by Country
11.2.2North America Cell Freezing Media Market by Product
11.2.3 North America Cell Freezing Media Market by Application
11.2.4 North America Cell Freezing Media Market by End User
11.2.5 USA
11.2.5.1 USA Cell Freezing Media Market by Product
11.2.5.2 USA Cell Freezing Media Market by Application
11.2.5.3 USA Cell Freezing Media Market by End User
11.2.6 Canada
11.2.6.1 Canada Cell Freezing Media Market by Product
11.2.6.2 Canada Cell Freezing Media Market by Application
11.2.6.3 Canada Cell Freezing Media Market by End User
11.2.7 Mexico
11.2.7.1 Mexico Cell Freezing Media Market by Product
11.2.7.2 Mexico Cell Freezing Media Market by Application
11.2.7.3 Mexico Cell Freezing Media Market by End User
11.3 Europe
11.3.1 Eastern Europe
11.3.1.1 Eastern Europe Cell Freezing Media Market by Country
11.3.1.2 Eastern Europe Cell Freezing Media Market by Product
11.3.1.3 Eastern Europe Cell Freezing Media Market by Application
11.3.1.4 Eastern Europe Cell Freezing Media Market by End User
11.3.1.5 Poland
11.3.1.5.1 Poland Cell Freezing Media Market by Product
11.3.1.5.2 Poland Cell Freezing Media Market by Application
11.3.1.5.3 Poland Cell Freezing Media Market by End User
11.3.1.6 Romania
11.3.1.6.1 Romania Cell Freezing Media Market by Product
11.3.1.6.2 Romania Cell Freezing Media Market by Application
11.3.1.6.4 Romania Cell Freezing Media Market by End User
11.3.1.7 Turkey
11.3.1.7.1 Turkey Cell Freezing Media Market by Product
11.3.1.7.2 Turkey Cell Freezing Media Market by Application
11.3.1.7.3 Turkey Cell Freezing Media Market by End User
11.3.1.8 Rest of Eastern Europe
11.3.1.8.1 Rest of Eastern Europe Cell Freezing Media Market by Product
11.3.1.8.2 Rest of Eastern Europe Cell Freezing Media Market by Application
11.3.1.8.3 Rest of Eastern Europe Cell Freezing Media Market by End User
11.3.2 Western Europe
11.3.2.1 Western Europe Cell Freezing Media Market by Product
11.3.2.2 Western Europe Cell Freezing Media Market by Application
11.3.2.3 Western Europe Cell Freezing Media Market by End User
11.3.2.4 Germany
11.3.2.4.1 Germany Cell Freezing Media Market by Product
11.3.2.4.2 Germany Cell Freezing Media Market by Application
11.3.2.4.3 Germany Cell Freezing Media Market by End User
11.3.2.5 France
11.3.2.5.1 France Cell Freezing Media Market by Product
11.3.2.5.2 France Cell Freezing Media Market by Application
11.3.2.5.3 France Cell Freezing Media Market by End User
11.3.2.6 UK
11.3.2.6.1 UK Cell Freezing Media Market by Product
11.3.2.6.2 UK Cell Freezing Media Market by Application
11.3.2.6.3 UK Cell Freezing Media Market by End User
11.3.2.7 Italy
11.3.2.7.1 Italy Cell Freezing Media Market by Product
11.3.2.7.2 Italy Cell Freezing Media Market by Application
11.3.2.7.3 Italy Cell Freezing Media Market by End User
11.3.2.8 Spain
11.3.2.8.1 Spain Cell Freezing Media Market by Product
11.3.2.8.2 Spain Cell Freezing Media Market by Application
11.3.2.8.3 Spain Cell Freezing Media Market by End User
11.3.2.9 Netherlands
11.3.2.9.1 Netherlands Cell Freezing Media Market by Product
11.3.2.9.2 Netherlands Cell Freezing Media Market by Application
11.3.2.9.3 Netherlands Cell Freezing Media Market by End User
11.3.2.10 Switzerland
11.3.2.10.1 Switzerland Cell Freezing Media Market by Product
11.3.2.10.2 Switzerland Cell Freezing Media Market by Application
11.3.2.10.3 Switzerland Cell Freezing Media Market by End User
11.3.2.11.1 Austria
11.3.2.11.2 Austria Cell Freezing Media Market by Product
11.3.2.11.3 Austria Cell Freezing Media Market by Application
11.3.2.11.4 Austria Cell Freezing Media Market by End User
11.3.2.12 Rest of Western Europe
11.3.2.12.1 Rest of Western Europe Cell Freezing Media Market by Product
11.3.2.12.2 Rest of Western Europe Cell Freezing Media Market by Application
11.3.2.12.3 Rest of Western Europe Cell Freezing Media Market by End User
11.4 Asia-Pacific
11.4.1 Asia-Pacific Cell Freezing Media Market by Country
11.4.2 Asia-Pacific Cell Freezing Media Market by Product
11.4.3 Asia-Pacific Cell Freezing Media Market by Application
11.4.4 Asia-Pacific Cell Freezing Media Market by End User
11.4.5 China
11.4.5.1 China Cell Freezing Media Market by Product
11.4.5.2 China Cell Freezing Media Market by End User
11.4.5.3 China Cell Freezing Media Market by Application
11.4.6 India
11.4.6.1 India Cell Freezing Media Market by Product
11.4.6.2 India Cell Freezing Media Market by Application
11.4.6.3 India Cell Freezing Media Market by End User
11.4.7 Japan
11.4.7.1 Japan Cell Freezing Media Market by Product
11.4.7.2 Japan Cell Freezing Media Market by Application
11.4.7.3 Japan Cell Freezing Media Market by End User
11.4.8 South Korea
11.4.8.1 South Korea Cell Freezing Media Market by Product
11.4.8.2 South Korea Cell Freezing Media Market by Application
11.4.8.3 South Korea Cell Freezing Media Market by End User
11.4.9 Vietnam
11.4.9.1 Vietnam Cell Freezing Media Market by Product
11.4.9.2 Vietnam Cell Freezing Media Market by Application
11.4.9.3 Vietnam Cell Freezing Media Market by End User
11.4.10 Singapore
11.4.10.1 Singapore Cell Freezing Media Market by Product
11.4.10.2 Singapore Cell Freezing Media Market by Application
11.4.10.3 Singapore Cell Freezing Media Market by End User
11.4.11 Australia
11.4.11.1 Australia Cell Freezing Media Market by Product
11.4.11.2 Australia Cell Freezing Media Market by Application
11.4.11.3 Australia Cell Freezing Media Market by End User
11.4.12 Rest of Asia-Pacific
11.4.12.1 Rest of Asia-Pacific Cell Freezing Media Market by Product
11.4.12.2 Rest of Asia-Pacific Cell Freezing Media Market by Application
11.4.12.3 Rest of Asia-Pacific Cell Freezing Media Market by End User
11.5 Middle East & Africa
11.5.1 Middle East
11.5.1.1 Middle East Cell Freezing Media Market by Country
11.5.1.2 Middle East Cell Freezing Media Market by Product
11.5.1.3 Middle East Cell Freezing Media Market by Application
11.5.1.4 Middle East Cell Freezing Media Market by End User
11.5.1.5 UAE
11.5.1.5.1 UAE Cell Freezing Media Market by Product
11.5.1.5.2 UAE Cell Freezing Media Market by Application
11.5.1.5.3 UAE Cell Freezing Media Market by End User
11.5.1.6 Egypt
11.5.1.6.1 Egypt Cell Freezing Media Market by Product
11.5.1.6.2 Egypt Cell Freezing Media Market by Application
11.5.1.6.3 Egypt Cell Freezing Media Market by End User
11.5.1.7 Saudi Arabia
11.5.1.7.1 Saudi Arabia Cell Freezing Media Market by Product
11.5.1.7.2 Saudi Arabia Cell Freezing Media Market by Application
11.5.1.7.3 Saudi Arabia Cell Freezing Media Market by End User
11.5.1.8 Qatar
11.5.1.8.1 Qatar Cell Freezing Media Market by Product
11.5.1.8.2 Qatar Cell Freezing Media Market by Application
11.5.1.8.3 Qatar Cell Freezing Media Market by End User
11.5.1.9 Rest of Middle East
11.5.1.9.1 Rest of Middle East Cell Freezing Media Market by Product
11.5.1.9.2 Rest of Middle East Cell Freezing Media Market by Application
11.5.1.9.3 Rest of Middle East Cell Freezing Media Market by End User
11.5.2 Africa
11.5.2.1 Africa Transfusion Diagnostics Market by Country
11.5.2.2 Africa Cell Freezing Media Market by Product
11.5.2.3 Africa Cell Freezing Media Market by Application
11.5.2.4 Africa Cell Freezing Media Market by End User
11.5.2.5 Nigeria
11.5.2.5.1 Nigeria Cell Freezing Media Market by Product
11.5.2.5.2 Nigeria Cell Freezing Media Market by Application
11.5.2.5.3 Nigeria Cell Freezing Media Market by End User
11.5.2.6 South Africa
11.5.2.6.1 South Africa Cell Freezing Media Market by Product
11.5.2.6.2 South Africa Cell Freezing Media Market by Application
11.5.2.6.3 South Africa Cell Freezing Media Market by End User
11.5.2.7 Rest of Africa
11.5.2.7.1 Rest of Africa Cell Freezing Media Market by Product
11.5.2.7.2 Rest of Africa Cell Freezing Media Market by Application
11.5.2.7.3 Rest of Africa Cell Freezing Media Market by End User
11.6 Latin America
11.6.1 Latin America Cell Freezing Media Market by Country
11.6.2 Latin America Cell Freezing Media Market by Product
11.6.3 Latin America Cell Freezing Media Market by Application
11.6.4 Latin America Cell Freezing Media Market by End User
11.6.5 Brazil
11.6.5.1 Brazil Cell Freezing Media Market by Product
11.6.5.2 Brazil Cell Freezing Media Market by Application
11.6.5.3 Brazil Cell Freezing Media Market by End User
11.6.6 Argentina
11.6.6.1 Argentina Cell Freezing Media Market by Product
11.6.6.2 Argentina Cell Freezing Media Market by Application
11.6.6.3 Argentina Cell Freezing Media Market by End User
11.6.7 Colombia
11.6.7.1 Colombia Cell Freezing Media Market by Product
11.6.7.2 Colombia Cell Freezing Media Market by Application
11.6.7.3 Colombia Cell Freezing Media Market by End User
11.6.8 Rest of Latin America
11.6.8.1 Rest of Latin America Cell Freezing Media Market by Product
11.6.8.2 Rest of Latin America Cell Freezing Media Market by Application
11.6.8.3 Rest of Latin America Cell Freezing Media Market by End User
12. Company profile
12.1 Thermo Fisher Scientific, Inc.
12.1.1 Company Overview
12.1.2 Financial
12.1.3 Products/ Services Offered
12.1.4 SWOT Analysis
12.1.5 The SNS View
12.2 Merck KGaA
12.2.1 Company Overview
12.2.2 Financials
12.2.3 Product/Services Offered
12.2.4 SWOT Analysis
12.2.5 The SNS View
12.3 Sartorius AG
12.3.1 Company Overview
12.3.2 Financials
12.3.3 Product/Services Offered
12.3.4 SWOT Analysis
12.3.5 The SNS View
12.4 BioLife Solutions, Inc.
12.4.1 Company Overview
12.4.2 Financials
12.4.3 Product/Services Offered
12.4.4 SWOT Analysis
12.4.5 The SNS View
12.5 Bio-Techne
12.5.1 Company Overview
12.5.2 Financials
12.5.3 Product/Services Offered
12.5.4 SWOT Analysis
12.5.5 The SNS View
12.6 HiMedia Laboratories
12.6.1 Company Overview
12.6.2 Financials
12.6.3 Product/Services Offered
12.6.4 SWOT Analysis
12.6.5 The SNS View
12.7 PromoCell GmbH
12.7.1 Company Overview
12.7.2 Financials
12.7.3 Product/Services Offered
12.7.4 SWOT Analysis
12.7.5 The SNS View
12.8 Capricorn Scientific
12.8.1 Company Overview
12.8.2 Financials
12.8.3 Product/Services Offered
12.8.4 SWOT Analysis
12.8.5 The SNS View
12.9 Cell Applications, Inc.
12.9.1 Company Overview
12.9.2 Financials
12.9.3 Product/Services Offered
12.9.4 SWOT Analysis
12.9.5 The SNS View
12.10 STEMCELL Technologies.
12.10.1 Company Overview
12.10.2 Financials
12.10.3 Product/Services Offered
12.10.4 SWOT Analysis
12.10.5 The SNS View
12.11 AMSBIO
12.11.1 Company Overview
12.11.2 Financials
12.11.3 Product/Services Offered
12.11.4 SWOT Analysis
12.11.5 The SNS View
12.12 Cell Systems
12.12.1 Company Overview
12.12.2 Financials
12.12.3 Product/Services Offered
12.12.4 SWOT Analysis
12.12.5 The SNS View
12.13 BPS Bioscience, Inc.
12.13.1 Company Overview
12.13.2 Financials
12.13.3 Product/Services Offered
12.13.4 SWOT Analysis
12.13.5 The SNS View
13. Competitive Landscape
13.1 Competitive Benchmarking
13.2 Market Share Analysis
13.3 Recent Developments
13.3.1 Industry News
13.3.2 Company News
13.3.3 Mergers & Acquisitions
14. Use Case and Best Practices
15. Conclusion
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